FBXO41 Polyclonal antibody, PBS Only

FBXO41 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 24519-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 24519-1-AP (same clone as 24519-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24519-1-AP (FBXO41 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24519-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 24519-1-AP (same clone as 24519-1-PBS)

  IP result of anti-FBXO41 (IP:24519-1-AP, 4ug; Detection:24519-1-AP 1:1000) with mouse brain tissue lysate 6000ug. This data was developed using the same antibody clone with 24519-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 24519-1-AP (same clone as 24519-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24519-1-AP (FBXO41 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24519-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 24519-1-AP (same clone as 24519-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24519-1-AP (FBXO41 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24519-1-PBS in a different storage buffer formulation.

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Product Information

24519-1-PBS targets FBXO41 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: FBXO41 fusion protein Ag21595
• Full Name: F-box protein 41
• Calculated Molecular Weight: 875 aa, 94 kDa
• Observed Molecular Weight: 100 kDa
• GenBank Accession Number: BC112202
• Gene Symbol: FBXO41
• Gene ID (NCBI): 150726
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

FBXO41 also named as F box only protein 41 is a 875 amino-acid protein, which directly interact with SKP1 and CUL1. FBXO41 is identified as a Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, which as a regulator mediates some protein ubiquitination degradation. FBXO41 consists of F-box domain and has zinc ion binding activity. FBXO41 may have an association with Parkinson's disease.