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  • Featured Product
  • KD/KO Validated

FAM107A Polyclonal antibody, PBS Only

FAM107A Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 12176-1-PBS

Synonyms

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human lung cancer tissue using FAM107A Polyclonal antibody (12176-1-AP)

    IHC staining of human lung cancer using 12176-1-AP (same clone as 12176-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 12176-1-AP (FAM107A antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12176-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using FAM107A Polyclonal antibody (12176-1-AP)

    IHC staining of human lung cancer using 12176-1-AP (same clone as 12176-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 12176-1-AP (FAM107A antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12176-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of MCF-7 cells using FAM107A Polyclonal antibody (12176-1-AP)

    IF Staining of MCF-7 using 12176-1-AP (same clone as 12176-1-PBS)

    Immunofluorescent analysis of MCF-7 cells, using FAM107A antibody 12176-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). This data was developed using the same antibody clone with 12176-1-PBS in a different storage buffer formulation.

Product Information

12176-1-PBS targets FAM107A in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FAM107A fusion protein Ag2820
Full Name family with sequence similarity 107, member A
Calculated Molecular Weight 144 aa, 17 kDa
GenBank Accession NumberBC010561
Gene Symbol FAM107A
Gene ID (NCBI) 11170
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

FAM107A, also named as TU3A, encodes a 144 amino-acid protein, which contains a coiled-coil domain and a nuclear localization signal. FAM107A as a transcription factor regulates some gene transcription and signal transduction in cell. With the exception of peripheral blood cells, FAM107A is widely expressed in normal tissues, but shows significant loss of expression in renal cell carcinomas and frequent loss of expression in cervical, gastric, ovarian and non small cell lung cancers. Transfection of FAM107A mRNA into cancer cell line inhibits cell growth and proliferation, supporting the evidence that the gene functions as an important tumor suppressor.