FADS2-Specific Recombinant antibody, PBS Only

• 

  IF Staining of HepG2 using 84527-5-RR (same clone as 84527-5-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using FADS2-Specific antibody (84527-5-RR, Clone: 241863G3 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84527-5-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 84527-5-RR

  Biolayer interferometry (BLl) kinetic assays of 84527-5-RR against Human FADS2-Specific were performed. The affinity constant is below 1 pM.

FADS2-Specific Uni-rAb^TM Recombinant Antibody for IF/ICC, Indirect ELISA

Cat No. 84527-5-PBS

Clone No.241863G3

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Indirect ELISA

Synonyms

FADS2, EC:1.14.19.3, Delta-6 desaturase, D6D, Acyl-CoA 6-desaturase

---

Product Information

84527-5-PBS targets FADS2-Specific in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: FADS2-Specific fusion protein Ag27715
• Full Name: fatty acid desaturase 2
• Calculated Molecular Weight: 445 aa, 49 kDa
• GenBank Accession Number: BC009011
• Gene Symbol: FADS2
• Gene ID (NCBI): 9415
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: O95864
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Fatty acid desaturase 2 (FADS2) is responsible for the first desaturation reaction in the synthesis of highly unsaturated fatty acids (HUFAs), such as arachidonic acid (20:4n-6) and eicosapentaenoic acid (20:5n-3), and is involved in Mead acid (20:3n-9) production during essential fatty acid deficiency (EFAD) (PMID: 29353041). This is important when temperatures changes and the membrane is under distress. It has 4 isoforms and can be detected as 46-52 kDa.