FAAP100 Polyclonal antibody, PBS Only

• 

  WB analysis using 31841-1-AP (same clone as 31841-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31841-1-AP (FAAP100 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31841-1-PBS in a different storage buffer formulation.

FAAP100 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 31841-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

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Product Information

31841-1-PBS targets FAAP100 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: FAAP100 fusion protein Ag36385
• Full Name: chromosome 17 open reading frame 70
• Calculated Molecular Weight: 93 kDa
• Observed Molecular Weight: 100 kDa
• GenBank Accession Number: BC117139
• Gene Symbol: C17orf70
• Gene ID (NCBI): 80233
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q0VG06
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

FA core complex associated protein 100 (FAAP100, also known as C17orf70) is a component of the Fanconi anemia (FA), which plays a role in the FA-associated DNA damage response network as well as regulates Fanconi anemia group D2 protein (FANCD2) monoubiquitination and the stability of the FA core complex (PMID: 17396147). FAAP100 deletion leads to FA pathway inactivation, increases TRCs and cotranscriptional R-loops, and contributes to the collapse of replication forks and the generation of DNA damage (PMID: 37580696).