Tested Applications
Positive WB detected in | HEK-293 cells, HeLa cells, K-562 cells, SW480 cells, RAW 264.7 cells |
Positive FC (Intra) detected in | HeLa cells |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:2000-1:17000 |
Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
84449-1-RR targets Exportin 4 in WB, FC (Intra), ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Exportin 4 fusion protein Ag21845 Predict reactive species |
Full Name | exportin 4 |
Calculated Molecular Weight | 1151 aa, 130 kDa |
Observed Molecular Weight | 130 kDa |
GenBank Accession Number | BC113571 |
Gene Symbol | Exportin 4/XPO4 |
Gene ID (NCBI) | 64328 |
RRID | AB_3671975 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q9C0E2 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
exportin 4 (XPO4) maps to chromosome 13q and belongs to the importin β family which acts as a bidirectional nuclear transport receptor. Decreased XPO4 expression has been shown to associate with hepatocellular carcinoma. A genome-wide copy number variation (CNV) association study in a small cohort of Malaysian subjects identified a CNV in XPO4 to be correlated with the progression of metabolic (dysfunction) associated fatty liver disease (MAFLD). (PMID: 34388518)
Protocols
Product Specific Protocols | |
---|---|
WB protocol for Exportin 4 antibody 84449-1-RR | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |