Product Information
84449-1-PBS targets Exportin 4 in WB, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Exportin 4 fusion protein Ag21845 Predict reactive species |
Full Name | exportin 4 |
Calculated Molecular Weight | 1151 aa, 130 kDa |
Observed Molecular Weight | 130 kDa |
GenBank Accession Number | BC113571 |
Gene Symbol | Exportin 4/XPO4 |
Gene ID (NCBI) | 64328 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q9C0E2 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
exportin 4 (XPO4) maps to chromosome 13q and belongs to the importin β family which acts as a bidirectional nuclear transport receptor. Decreased XPO4 expression has been shown to associate with hepatocellular carcinoma. A genome-wide copy number variation (CNV) association study in a small cohort of Malaysian subjects identified a CNV in XPO4 to be correlated with the progression of metabolic (dysfunction) associated fatty liver disease (MAFLD). (PMID: 34388518)