EXOSC7 Monoclonal antibody, PBS Only

EXOSC7 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, pig, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2A4C6

Cat no : 68456-1-PBS

Synonyms

KIAA0116, hRrp42p, Exosome component 7, Exosome complex component RRP42, EAP1

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Validation Data Gallery

• 

  WB analysis using 68456-1-Ig (same clone as 68456-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68456-1-Ig (EXOSC7 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68456-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68456-1-Ig (same clone as 68456-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68456-1-Ig (EXOSC7 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68456-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68456-1-Ig (same clone as 68456-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68456-1-Ig (EXOSC7 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68456-1-PBS in a different storage buffer formulation.

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Product Information

68456-1-PBS targets EXOSC7 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.

• Tested Reactivity: human, mouse, rat, pig, rabbit
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: EXOSC7 fusion protein Ag18322
• Full Name: exosome component 7
• Calculated Molecular Weight: 291 aa, 32 kDa
• Observed Molecular Weight: 35 kDa
• GenBank Accession Number: BC012831
• Gene Symbol: EXOSC7
• Gene ID (NCBI): 23016
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. EXOSC7 also named as RRP42 or EAP1 is a 291 amino acid protein, which belongs to the RNase PH family. EXOSC7 is one of the six RNase-PH domain subunits of the exosome and required for the processing of the 7S pre-RNA.