ERp57/ERp60 Monoclonal antibody, PBS Only

ERp57/ERp60 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66423-1-PBS
Clone No.3G4G7

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

ERp57, PDIA3, ER60, EC:5.3.4.1, Disulfide isomerase ER-60

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

66423-1-PBS targets ERp57/ERp60 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen ERp57/ERp60 fusion protein Ag8741 Predict reactive species
Full Name protein disulfide isomerase family A, member 3
Calculated Molecular Weight 505 aa, 57 kDa
Observed Molecular Weight 57 kDa, 60 kDa
GenBank Accession NumberBC014433
Gene Symbol PDIA3
Gene ID (NCBI) 2923
RRIDAB_2881795
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP30101
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

PDIA3, also named as P58, ER60, ERp57, ERp60, ERp61, GRP57, GRP58 and PI-PLC, is a member of the PDI family, participates in the oxidation, reduction, and isomerization of disulfide bonds for correct folding of secretory proteins before modification and transport in the endoplasmic reticulum. It is associated with apoptosis or inhibition of cancer cell growth. PDIA3 was once thought to be a phospholipase; however, it has been demonstrated that this protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and PDIA3 mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

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