ERCC1 Monoclonal antibody, PBS Only
ERCC1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
WB, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1H4D5
Cat no : 66275-1-PBS
Synonyms
Validation Data Gallery
Product Information
66275-1-PBS targets ERCC1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | ERCC1 fusion protein Ag6417 |
Full Name | excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) |
Calculated Molecular Weight | 33 kDa |
Observed Molecular Weight | 38 kDa |
GenBank Accession Number | BC052813 |
Gene Symbol | ERCC1 |
Gene ID (NCBI) | 2067 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Excision Repair Cross Complementing 1 (ERCC1) is a structure-specific endonuclease that is responsible for the 5'-incision during DNA repair. It forms a complex with ERCC11, XPF and ERCC4, which are required in both recombinatorial repair and nucleotide excision repair. It has been found that ERCC1, together with RRM1, are determinants of survival after surgical treatment of early-stage, non-small-cell lung cancer. (Ref: Simon, ER. 2005)