ERBB2IP Monoclonal antibody, PBS Only

• Featured Product
• KD/KO Validated

ERBB2IP Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A8D4

Cat no : 68159-1-PBS

Synonyms

Densin 180 like protein, erbb2 interacting protein, ERBB2IP, ERBIN, KIAA1225, LAP2, Protein LAP2

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Validation Data Gallery

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  WB analysis using 68159-1-Ig (same clone as 68159-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68159-1-Ig (ERBB2IP antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68159-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68159-1-Ig (same clone as 68159-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68159-1-Ig (ERBB2IP antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68159-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 68159-1-Ig (same clone as 68159-1-PBS)

  WB result of ERBB2IP antibody (68159-1-Ig; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-ERBB2IP transfected HeLa cells. This data was developed using the same antibody clone with 68159-1-PBS in a different storage buffer formulation.

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Product Information

68159-1-PBS targets ERBB2IP in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

• Tested Reactivity: Human, mouse, rat
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: ERBB2IP fusion protein Ag18514
• Full Name: erbb2 interacting protein
• Calculated Molecular Weight: 1412 aa, 158 kDa
• Observed Molecular Weight: 150-180 kDa
• GenBank Accession Number: BC115012
• Gene Symbol: ERBB2IP
• Gene ID (NCBI): 55914
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

ERBB2IP is a cytoplasmic protein that contains leucine-rich repeats (LRR) and PSD95/Dlg1/zo-1 (PDZ) domain (thus named a LAP protein). ERBB2IP interacts, via its single PDZ domain, specifically with ErbB2, but not with ErbB3, ErbB4, or EGFR. It is colocalized with ErbB2 at the basolateral membranes of epithelial cells. In addition, ERBB2IP also interacts with PSD‐95, Lano and with three p120‐related catenins, eBPAG1 and the β4 subunit of the α6β4 integrin, two major components of hemidesmosomes. The molecular weight of ERBB2IP was predicted 150~180 kDa by Western Blot.(PMID: 25288731,PMID: 24252174,PMID: 19289088)