Product Information
66975-1-PBS targets EPO/Erythropoietin in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | EPO/Erythropoietin fusion protein Ag23054 Predict reactive species |
Full Name | erythropoietin |
Calculated Molecular Weight | 193 aa, 21 kDa |
GenBank Accession Number | BC093628 |
Gene Symbol | EPO/Erythropoietin |
Gene ID (NCBI) | 2056 |
RRID | AB_2882295 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P01588 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Erythropoietin (Epo) is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. Its effect is realized by binding erythropoietin receptor (EpoR) expressed on erythroid progenitor cells. EpoR, is a glycoprotein expressed on megakaryocytes, erythroid progenitors and endothelial cells. Epo also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.