Product Information
68065-1-PBS targets EEA1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | EEA1 fusion protein Ag28814 Predict reactive species |
Full Name | early endosome antigen 1 |
Calculated Molecular Weight | 162 kDa |
Observed Molecular Weight | 162 kDa |
GenBank Accession Number | NM_003566 |
Gene Symbol | EEA1 |
Gene ID (NCBI) | 8411 |
RRID | AB_2918806 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q15075 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Early endosome antigen 1 (EEA1) is a marker of early endosomes and has an important role in endosomal trafficking. EEA1 contains coiled-coil regions and an FYVE-type zinc finger which interacts with phosphatidylinositol-3-phosphate. EEA1 functions as a Rab5 effector, mediates endosome docking and, together with SNAREs, leads to membrane fusion.