Dynamitin (1-401 AA) Monoclonal antibody, PBS Only

Dynamitin (1-401 AA) Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 60257-1-PBS
Clone No.2B9A5

Host / Isotype

Mouse / IgG3

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

DCTN 50, DCTN2, DCTN50, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, Dynamitin, Dynamitin (1-401 AA), p50 dynamitin, RBP50

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

60257-1-PBS targets Dynamitin (1-401 AA) in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Mouse / IgG3
Class Monoclonal
Type Antibody
Immunogen Dynamitin (1-401 AA) fusion protein Ag1902 Predict reactive species
Full Name dynactin 2 (p50)
Calculated Molecular Weight 401 aa, 44 kDa
Observed Molecular Weight 52+150 kDa
GenBank Accession NumberBC014083
Gene Symbol Dynamitin
Gene ID (NCBI) 10540
RRIDAB_2881378
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ13561
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believed to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, thus extend to vesicle trafficking and membrane integrity. Dynamitin was named so because its overexpression causes dynactin complex which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is for MacMARCKS binding and residues 59-83 is responsible for calmodulin binding. This antibody is is against the N terminal 86aa of full length p50 dynamitin.

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