- Featured Product
- KD/KO Validated
MKP-2/DUSP4 Polyclonal antibody
MKP-2 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (1)
Applications
WB, IHC, ELISA
Conjugate
Unconjugated
Cat no : 10739-1-AP
Synonyms
Validation Data Gallery
Published Applications
| KD/KO | See 1 publications below |
| WB | See 2 publications below |
| IHC | See 1 publications below |
Product Information
10739-1-AP targets MKP-2 in WB, IHC, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | MKP-2 fusion protein Ag1206 |
| Full Name | dual specificity phosphatase 4 |
| Calculated Molecular Weight | 43 kDa |
| GenBank Accession Number | BC014565 |
| Gene Symbol | DUSP4 |
| Gene ID (NCBI) | 1846 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
DUSP4, also named as MKP-2, is a member of the mitogen-activated protein (MAP) kinase phosphatase family which has been suggested to play an important role in the feedback control of MAP kinase-mediated gene expression. DUSP4 preferentially inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.
Publications
| Species | Application | Title |
|---|---|---|
J Clin Invest Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis.
| ||
Cell Death Discov NR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving. |
