CoraLite® Plus 488-conjugated DSP Monoclonal antibody
DSP Monoclonal Antibody for
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1B10D4
Cat no : CL488-68364
Synonyms
Validation Data Gallery
Product Information
CL488-68364 targets DSP in applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | DSP fusion protein Ag30499 |
| Full Name | desmoplakin |
| Calculated Molecular Weight | 2871 aa, 332 kDa |
| Observed Molecular Weight | 240-330 kDa |
| GenBank Accession Number | BC140802 |
| Gene Symbol | DSP |
| Gene ID (NCBI) | 1832 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
The desmoplakin (DP) is the most abundant desmosomal proteins and is located at the cytoplasmic portion of the desmosomes which are specialized cell-cell adhesion structures abundant in tissues such as muscle and epidermis that are subjected to mechanical stress. Desmoplakin 1 and 2 (DP 1 and 2) are two splice variants sharing common C-terminal and N-terminal globular head and tail domains, but differ in the length of the rod domain that links them. This antibody detects both DP1 (280-330 kDa) and DP2 (240-260 kDa). (PMID: 16467215, 11781569)
