Desmin Monoclonal antibody

Desmin Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, pig and More (2)

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

CloneNo.

3E12C8

Cat no : 60226-1-Ig

Synonyms

CMD1I, CSM1, CSM2, DES, desmin



Tested Applications

Positive WB detected inHuman heart, human testis tissue, human heart tissue, human placenta tissue, pig heart tissue, pig colon tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Product Information

60226-1-Ig targets Desmin in WB, IHC, IF, ELISA applications and shows reactivity with human, pig samples.

Tested Reactivity human, pig
Cited Reactivityhuman, mouse, rat
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen Desmin fusion protein Ag9675
Full Name desmin
Calculated molecular weight 470 aa, 54 kDa
Observed molecular weight 55 kDa
GenBank accession numberBC032116
Gene symbol DES
Gene ID (NCBI) 1674
RRIDAB_11042773
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Desmin is the main intermediate filament protein in skeletal and cardiac muscle cells and is essential for both the structural integrity and the survival of muscle cells. As an abundant muscle-specific protein, desmin has been widely used as a marker of muscle derived tumors. Anti-desmin is also valuable in the differential diagnosis of tumors of uncertain origin.

Protocols

Product Specific Protocols
WB protocol for Desmin antibody 60226-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Br J Pharmacol

Catalpol Alleviates Adriamycin-Induced Nephropathy by Activating the SIRT1 Signalling Pathway In Vivo and In Vitro.

Authors - Jiangnan Zhang
ratIF

Diabetes Metab Res Rev

Gene expression profiles of rat MMECs with different glucose levels and fgl2 gene silencing.

Authors - Zhenzhong Zheng
mouseIHC

Exp Cell Res

Effect of sarcolipin-mediated cell transdifferentiation in sarcopenia-associated skeletal muscle fibrosis.

Authors - Qiu-Nan Chen
humanIF

Exp Eye Res

Botox-A improve the thyroid-associated ophthalmopathy (TAO) orbital fibroblast activation through inhibiting the TGF-β/Smad signaling.

Authors - Xin Qi
humanIF

Reprod Biomed Online

Stomatin-like protein 2 is involved in endometrial stromal cell proliferation and differentiation during decidualization in mice and humans.

Authors - Qian Feng
mouseWB

BMC Nephrol

Adiponectin protects obesity-related glomerulopathy by inhibiting ROS/NF-κB/NLRP3 inflammation pathway.

Authors - Xiaohong Xu