Product Information
12094-1-PBS targets DDIT4L in WB, Indirect ELISA applications and shows reactivity with mouse samples.
Tested Reactivity | mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | DDIT4L fusion protein Ag2735 Predict reactive species |
Full Name | DNA-damage-inducible transcript 4-like |
Calculated Molecular Weight | 193 aa, 22 kDa |
Observed Molecular Weight | 22 kDa |
GenBank Accession Number | BC013592 |
Gene Symbol | DDIT4L |
Gene ID (NCBI) | 115265 |
RRID | AB_2918027 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q96D03 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
DNA-damage-inducible transcript 4-like protein(DDIT4L), encoded by the stress responsive gene REDD2, is a negative regulator of mTOR signaling, and expressed predominantly in skeletal muscle. It regulates the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Also, DDIT4L involves in oxidized low-density lipoprotein-induced macrophage death sensitivity.