DDAH2 Monoclonal antibody, PBS Only
DDAH2 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG3
Reactivity
Human, Rat, Mouse, Rabbit
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1A10G3
Cat no : 68154-1-PBS
Synonyms
Validation Data Gallery
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
68154-1-PBS targets DDAH2 in WB, Indirect ELISA applications and shows reactivity with Human, Rat, Mouse, Rabbit samples.
Tested Reactivity | Human, Rat, Mouse, Rabbit |
Host / Isotype | Mouse / IgG3 |
Class | Monoclonal |
Type | Antibody |
Immunogen | DDAH2 fusion protein Ag7127 |
Full Name | dimethylarginine dimethylaminohydrolase 2 |
Calculated Molecular Weight | 29 kDa |
Observed Molecular Weight | 30 kDa |
GenBank Accession Number | BC001435 |
Gene Symbol | DDAH2 |
Gene ID (NCBI) | 23564 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
The DDAH family of proteins is formed by two isoforms, DDAH-1 and DDAH-2, both of which utilize ADMA as their substrate and increase NOS activity. DDAH-2,also named as DDAH, G6A, NG30, is the most prevalent isoform in blood vessels and endothelium and is important for embryonic development. It has also been linked to other diseases, such as hypertension, cerebral hemorrhage, cardiac disease, and diabetes. In cultured human endothelial cells,DDAH-2 had been found only in the cytosol, but in the nuclei of rat vascular smooth muscle cells.