Filter: AllIPIHC

IP experiment of mouse stomach using 66167-1-Ig (same clone as 66167-1-PBS)
IP result of anti-Claudin 18 (IP:66167-1-Ig, 3ug; Detection:66167-1-Ig 1:300) with mouse stomach tissue lysate 4000ug. This data was developed using the same antibody clone with 66167-1-PBS in a different storage buffer formulation.
IHC staining of human pancreas cancer using 66167-1-Ig (same clone as 66167-1-PBS)
Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 66167-1-Ig (Claudin 18 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66167-1-PBS in a different storage buffer formulation.
IHC staining of human stomach using 66167-1-Ig (same clone as 66167-1-PBS)
Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 66167-1-Ig (Claudin 18 antibody at dilution of 1:1000. This data was developed using the same antibody clone with 66167-1-PBS in a different storage buffer formulation.
IHC staining of human stomach using 66167-1-Ig (same clone as 66167-1-PBS)
Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 66167-1-Ig (Claudin 18 antibody at dilution of 1:1000. This data was developed using the same antibody clone with 66167-1-PBS in a different storage buffer formulation.
IHC staining of human pancreas cancer using 66167-1-Ig (same clone as 66167-1-PBS)
Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 66167-1-Ig (Claudin 18 antibody at dilution of 1:600 (under 10x lens). This data was developed using the same antibody clone with 66167-1-PBS in a different storage buffer formulation.
IHC staining of human pancreas cancer using 66167-1-Ig (same clone as 66167-1-PBS)
Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 66167-1-Ig (Claudin 18 antibody at dilution of 1:600 (under 40x lens). This data was developed using the same antibody clone with 66167-1-PBS in a different storage buffer formulation.
IHC staining of human ovary tumor using 66167-1-Ig (same clone as 66167-1-PBS)
Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 66167-1-Ig (Claudin 18 antibody at dilution of 1:1000. This data was developed using the same antibody clone with 66167-1-PBS in a different storage buffer formulation.
IHC staining of human ovary tumor using 66167-1-Ig (same clone as 66167-1-PBS)
Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 66167-1-Ig (Claudin 18 antibody at dilution of 1:1000. This data was developed using the same antibody clone with 66167-1-PBS in a different storage buffer formulation.
IHC staining of human stomach using 66167-1-Ig (same clone as 66167-1-PBS)
Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 66167-1-Ig (Claudin 18 antibody) at dilution of 1:600 (under 40x lens). This data was developed using the same antibody clone with 66167-1-PBS in a different storage buffer formulation.
IHC staining of human stomach using 66167-1-Ig (same clone as 66167-1-PBS)
Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 66167-1-Ig (Claudin 18 antibody at dilution of 1:600 (under 10x lens). This data was developed using the same antibody clone with 66167-1-PBS in a different storage buffer formulation.

Claudin 18 Monoclonal antibody, PBS Only

Claudin 18 Monoclonal Antibody for IHC, IP, Indirect ELISA

Cat No. 66167-1-PBS

Clone No.5G7F2

Review Product

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse

Applications

IHC, IP, Indirect ELISA

Synonyms

UNQ778/PRO1572, CLDN18, Claudin-18, Claudin18, 5G7F2

Formulation: PBS Only

PBS and Azide

PBS Only

Conjugate: Unconjugated

Size/Concentration:

-/ -

Freight/Packing: -

Quantity

- +

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Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

66167-1-PBS targets Claudin 18 in IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity	human, mouse
Host / Isotype	Mouse / IgG2a
Class	Monoclonal
Type	Antibody
Immunogen	Claudin 18 fusion protein Ag15517 Predict reactive species
Full Name	claudin 18
Calculated Molecular Weight	261 aa, 28 kDa
Observed Molecular Weight	29 kDa
GenBank Accession Number	BC146668
Gene Symbol	CLDN18
Gene ID (NCBI)	51208
RRID	AB_2881563
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	P56856
Storage Buffer	PBS Only
Storage Conditions	Store at -80°C.

Background Information

Claudin 18 (CLDN18) belongs to the large claudin family of proteins, which are tetraspan transmembrane proteins of tight junctions (PMID: 11585919; 18036336). Claudins exhibit specific patterns of expression in different tissues (PMID: 15447685). CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific (PMID: 11585919; 21832145). Altered CLDN18 expression has been reported in various human malignancies, including gastric cancer, lung adenocarcinoma, and pancreatic neoplasm (PMID: 17459057; 22076167; 21832145). This antibody can recognize both CLDN18.1 and CLDN18.2.