Product Information
67398-1-PBS targets Caspase 4 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | Caspase 4 fusion protein Ag29488 Predict reactive species |
Full Name | caspase 4, apoptosis-related cysteine peptidase |
Calculated Molecular Weight | 377 aa, 43 kDa |
Observed Molecular Weight | 43-48 kDa |
GenBank Accession Number | BC017839 |
Gene Symbol | Caspase 4 |
Gene ID (NCBI) | 837 |
RRID | AB_2882641 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P49662 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Caspase 4 (CASP4), is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.Caspase 4 is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. Overexpression of caspase 4 will induce cell apoptosis.