Product Information
60216-1-PBS targets CXCR7 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | CXCR7 fusion protein Ag14247 Predict reactive species |
Full Name | chemokine (C-X-C motif) receptor 7 |
Calculated Molecular Weight | 362 aa, 41 kDa |
Observed Molecular Weight | 50-60 kDa |
GenBank Accession Number | BC036661 |
Gene Symbol | CXCR7 |
Gene ID (NCBI) | 57007 |
RRID | AB_11182925 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P25106 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CXCR7 (C-X-C chemokine receptor type 7), also known as RDC1, is a member of the G-protein coupled receptor family. CXCR7 can bind the chemokines CXCL11 and CXCL12 with high affinity, and it also acts as a coreceptor with CXCR4 for a restricted number of HIV isolates. Expression of CXCR7 has been associated with cardiac development as well as with tumor growth and progression. This antibody recognizes endogenous CXCR7, which has an experimentally determined molecular weight of 50 kDa (PMID: 20197403; 20388803).