CXCR1 Recombinant antibody

CXCR1 Uni-rAb^TM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

240819A11

Cat no : 83801-4-RR

Synonyms

IL8RA, CDw128a, CD181, CD128, C C CKR 1

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Validation Data Gallery

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  WB analysis using 83801-4-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 83801-4-RR (CXCR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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  WB analysis of fetal human brain using 83801-4-RR

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 83801-4-RR (CXCR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: Jurkat cells, fetal human brain tissue, Raji cells, HepG2 cells

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

83801-4-RR targets CXCR1 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Peptide
• Full Name: interleukin 8 receptor, alpha
• Calculated Molecular Weight: 40 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: NM_000634
• Gene Symbol: CXCR1
• Gene ID (NCBI): 3577
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CXCR1, also named CMKAR1, IL8RA, and CD181, belongs to the G-protein coupled receptor 1 family. It is a receptor to interleukin-8, a powerful neutrophil chemotactic factor. The binding of IL-8 to the receptor causes activation of neutrophils. CXCR1 binds to IL-8 with a high affinity and MGSA (GRO) with a low affinity.