Product Information
68276-1-PBS targets CRTAC1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, rat, mouse, rabbit, pig samples.
Tested Reactivity | Human, rat, mouse, rabbit, pig |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | CRTAC1 fusion protein Ag32813 Predict reactive species |
Full Name | cartilage acidic protein 1 |
Calculated Molecular Weight | 661 aa, 71 kDa |
Observed Molecular Weight | 71 kDa |
GenBank Accession Number | BC034245 |
Gene Symbol | CRTAC1 |
Gene ID (NCBI) | 55118 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9NQ79 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CRTAC1 (cartilage acidic protein 1) is also named as ASPIC1 and CEP68. CRTAC1 is an extracellular matrix protein of human chondrogenic tissue. CRTAC1 promotes cell proliferation, migration and extracellular matrix regeneration and remodeling in primary human fibroblasts (PMID:32084494). CRTAC1 expression is decreased in tissue samples of bladder urothelial carcinoma (PMID:34818994). CRTAC1 overexpression promotes the pyroptosis of human lens epithelial cells by facilitating the reactive oxygen species (ROS) production in the formation of cataract (PMID:32838966). CRTAC1 was the most compelling and robust biomarker for osteoarthritis severity and progression (PMID:35924962).