Product Information
66072-1-PBS targets CPT1C in WB, IHC, Indirect ELISA applications and shows reactivity with human, pig samples.
Tested Reactivity | human, pig |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | CPT1C fusion protein Ag17963 Predict reactive species |
Full Name | carnitine palmitoyltransferase 1C |
Calculated Molecular Weight | 792 aa, 90 kDa |
Observed Molecular Weight | 82 kDa |
GenBank Accession Number | BC029104 |
Gene Symbol | CPT1C |
Gene ID (NCBI) | 126129 |
RRID | AB_11042325 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q8TCG5 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CPT1C, also named as CATL1, CPTI-B and B-CPTI, belongs to the carnitine/choline acetyltransferase family. Carnitine palmitoyltransferase (CPT) deficiencies are common disorders of mitochondrial fatty acid oxidation. The CPT system is made up of two separate proteins located in the outer (CPT1) and inner (CPT2) mitochondrial membranes. CPT1C is an active forms of related brain-type carnitine palmitoyltransferase I. CPT1C may be a regulated target of malonyl-CoA that relays the "malonyl-CoA signal" in hypothalamic neurons that express the orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. (PMID: 17018521 ) This antibody can bind the close sequences genes.