CPS1 Monoclonal antibody, PBS Only

CPS1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

2A12A4

Cat no : 67630-1-PBS

Synonyms

CPS1, CPSase I

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Validation Data Gallery

• 

  WB analysis of mouse liver using 67630-1-Ig (same clone as 67630-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 67630-1-Ig (CPS1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67630-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 67630-1-Ig (same clone as 67630-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 67630-1-Ig (CPS1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67630-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat liver using 67630-1-Ig (same clone as 67630-1-PBS)

  rat liver tissue were subjected to SDS PAGE followed by western blot with 67630-1-Ig (CPS1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67630-1-PBS in a different storage buffer formulation.

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Product Information

67630-1-PBS targets CPS1 in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.

• Tested Reactivity: Human, mouse, rat
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: carbamoyl-phosphate synthetase 1, mitochondrial
• Calculated Molecular Weight: 165 kDa
• Observed Molecular Weight: 140-165 kDa
• GenBank Accession Number: BC140943
• Gene Symbol: CPS1
• Gene ID (NCBI): 1373
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS only
• Storage Conditions: Store at -80°C.

Background Information

CPS1 is an enzyme that catalyzes the first committed step of the hepatic urea cycle, which is important in the removal of excess urea from cells. Expressed primarily in the liver and small intestine, CPS1 can be used as a marker for mitochondria in these tissues. In addition, CPS1 expression appears to be lost in adenocarcinomas of the small intestine.