COASY Monoclonal antibody, PBS Only

COASY Monoclonal Antibody for Indirect ELISA, IHC, WB
Cat No. 68358-1-PBS
Clone No.1D1C11

Host / Isotype

Mouse / IgG1

Reactivity

rat, mouse, human

Applications

Indirect ELISA, IHC, WB

Dephosphocoenzyme A kinase, Dephospho-CoA pyrophosphorylase, Dephospho-CoA kinase, Coenzyme A synthase, CoA synthase

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

68358-1-PBS targets COASY in Indirect ELISA, IHC, WB applications and shows reactivity with rat, mouse, human samples.

Tested Reactivity rat, mouse, human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen COASY fusion protein Ag33142 Predict reactive species
Full Name Coenzyme A synthase
Calculated Molecular Weight 564 aa, 62 kDa
Observed Molecular Weight 62 kDa
GenBank Accession NumberBC020985
Gene Symbol COASY
Gene ID (NCBI) 80347
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ13057
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Bifunctional coenzyme A synthase (COASY) is a bifunctional enzyme that catalyzes the fourth and fifth sequential steps of the CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation. It was reported that having a key role in erythroid maturation and identified upstream and downstream metabolites of COASY as a potential treatment for anemia in patients with MDS-RS (PMID: 36857430). COASY has 2 isoforms with molecular weights of 62 and 65 kDa.

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