Product Information
84580-4-PBS targets CD99 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Recombinant Protein Predict reactive species |
Full Name | CD99 molecule |
Calculated Molecular Weight | 19 kDa, 16 kDa, 17 kDa |
Observed Molecular Weight | 28 kDa, 32 kDa |
GenBank Accession Number | BC021620 |
Gene Symbol | CD99 |
Gene ID (NCBI) | 4267 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | P14209 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CD99, also known as MIC2, is a heavily O-glycosylated transmembrane protein involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. CD99 is broadly distributed on many cell types, with particularly strong expression on human cortical thymocytes, Ewing's sarcoma cells and peripheral primitive neuroectodermal tumors (PMID: 9794396; 16984917). In normal cells, CD99 has been functionally implicated in cell adhesion, migration, apoptosis, differentiation, activation, and proliferation of lymphocytes and monocyte extravasation and transport of several transmembrane proteins (PMID: 16984917).