Anti-Human CD93 Rabbit Recombinant Antibody

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  FC experiment of human PBMCs using 98337-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD93 Rabbit RecAb (98337-1-RR, Clone: 242464E6) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human PBMCs using 98337-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD93 Rabbit RecAb (98337-1-RR, Clone:242464E6)(red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

CD93 {ptg:Brand} Recombinant Antibody for FC

Cat No. 98337-1-RR

Clone No.242464E6

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

C1QR1, Matrix-remodeling-associated protein 4, C1qRp, C1qR(p), C1qR

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Tested Applications

• Positive FC detected in: human PBMCs

Recommended dilution

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98337-1-RR targets CD93 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: CD93 molecule
• Calculated Molecular Weight: 69 kDa
• GenBank Accession Number: NM_012072.3
• Gene Symbol: CD93
• Gene ID (NCBI): 22918
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9NPY3
• Storage Buffer: PBS with 0.09% sodium azide , pH 7.3
• Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.

Background Information

CD93, also known as C1qR or C1qR(p), is a single-pass type I transmembrane glycoprotein and a member of the group 14 of the C-type lectin-like domain (CTLD) superfamily, which also includes endosialin/CD248, thrombomodulin, and CLEC14A (PMID: 31287944). CD93 consists of a C-type lectin-like domain, five EGF-like repeats, a mucin-like domain, a transmembrane domain and a cytoplasmic domain (PMID: 28912033). CD93 is mainly expressed on endothelial cells and has been reported to be expressed by neurons and various cells of the hematopoietic system, including monocytes, neutrophils, B cells, natural killer cells, platelets and hematopoietic stem cells (PMID: 37443812). CD93 plays a role in various physiological processes including angiogenesis, inflammation, and cell adhesion (PMID: 31287944).