Anti-Human CD68 Rabbit Recombinant Antibody, PBS Only

CD68 Uni-rAb^TM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241810G1

Cat no : 98242-1-PBS

Synonyms

SCARD1, Macrosialin, GP110, CD68 molecule, 241810G1

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Validation Data Gallery

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  FC experiment of human PBMCs using 98242-1-RR (same clone as 98242-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD68 Rabbit Recombinant Antibody (98242-1-RR, Clone: 241810G1) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98242-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98242-1-RR (same clone as 98242-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD68 Rabbit Recombinant Antibody (98242-1-RR, Clone: 241810G1) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98242-1-PBS in a different storage buffer formulation.

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Product Information

98242-1-PBS targets CD68 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: CD68 molecule
• Calculated Molecular Weight: 37 kDa
• GenBank Accession Number: BC015557
• Gene Symbol: CD68
• Gene ID (NCBI): 968
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.