CD59 Monoclonal antibody, PBS Only
CD59 Monoclonal Antibody for WB, IHC, IF/ICC, IF-P, ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human
Applications
WB, IHC, IF/ICC, IF-P, ELISA
Conjugate
Unconjugated
CloneNo.
1E3A1
Cat no : 68222-1-PBS
Synonyms
Validation Data Gallery
Product Information
68222-1-PBS targets CD59 in WB, IHC, IF/ICC, IF-P, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | CD59 fusion protein Ag32834 |
Full Name | CD59 molecule, complement regulatory protein |
Calculated Molecular Weight | 19 kDa |
Observed Molecular Weight | 18-25 kDa |
GenBank Accession Number | BC001506 |
Gene Symbol | CD59 |
Gene ID (NCBI) | 966 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CD59, also named as MIC11, MIN1, MIN2, MIN3, MSK21, MIRL, MACIF, HRF20 and 1F5 antigen, is a cell surface molecule glycoprotein with MW 18-25 kDa. It acts as a determinant of proximal-distal cell identity. CD59 acts by binding to the C8 and/or C9 complements of the assembling membrane attack complex (MAC), thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. It is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.