CD40L/CD154 Recombinant antibody, PBS Only

• 

  WB analysis of human peripheral blood platelets using 85209-4-RR (same clone as 85209-4-PBS)

  human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 85209-4-RR (CD40L/CD154 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85209-4-PBS in a different storage buffer formulation.

CD40L/CD154 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 85209-4-PBS

Clone No.242847A5

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

CD154, CD40L; CD154, CD40LG, CD40 ligand, CD40 L

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Product Information

85209-4-PBS targets CD40L/CD154 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: CD40 ligand
• Calculated Molecular Weight: 261 aa, 29 kDa
• Observed Molecular Weight: 30 kDa
• GenBank Accession Number: BC071754
• Gene Symbol: CD40 Ligand
• Gene ID (NCBI): 959
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P29965
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

The CD40 ligand (CD40L, TRAP, CD154), a member of the TNF superfamily of ligands, is expressed as either a 33 kDa transmembrane homologue or an 18 kDa soluble form (sCD154). CD40L is primarily expressed on activated CD4+ T cells and a small proportion of CD8+ T cells and platelets. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. Recent studies have suggested that CD40/CD40L interactions regulate oxidative stress and affect various signaling pathways in both the immunological and the cardiovascular systems. The CD40/CD40L system is also involved in tumorigenesis.