Product Information
98002-2-PBS targets CD226 in FC applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Fusion Protein Predict reactive species |
Full Name | CD226 molecule |
Calculated Molecular Weight | 336 aa, 39 kDa |
GenBank Accession Number | BC074787 |
Gene Symbol | CD226 |
Gene ID (NCBI) | 10666 |
ENSEMBL Gene ID | ENSG00000150637 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q15762 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).