Anti-Mouse CD11a (M17/4)

CD11a Monoclonal Antibody for FC

Host / Isotype

Rat / IgG2a, kappa

Reactivity

Mouse

Applications

FC

Conjugate

Unconjugated

CloneNo.

M17/4

Cat no : 65177-1-Ig

Synonyms

Cd11a, integrin alpha L, Itgal, LFA 1, Ly 15, Ly 21



Tested Applications

Positive FC detected inmouse thymocytes

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

65177-1-Ig targets CD11a in FC applications and shows reactivity with Mouse samples.

Tested Reactivity Mouse
Host / Isotype Rat / IgG2a, kappa
Class Monoclonal
Type Antibody
Immunogen C57BL/6 mouse splenic secondary cytotoxic T cells
Full Name integrin alpha L
GenBank Accession NumberBC145802
Gene Symbol CD11a
Gene ID (NCBI) 16408
RRIDAB_2918452
Conjugate Unconjugated
Form Liquid
Purification MethodPurified by protein-A affinity chromatography
Storage Buffer PBS with 0.09% sodium azide.
Storage ConditionsStore at 2-8°C. Stable for one year after shipment.

Background Information

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).

Protocols

Product Specific Protocols
FC protocol for CD11a antibody 65177-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols