Anti-Mouse IFNGR1/CD119 Rabbit Recombinant Antibody

IFNGR1/CD119 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98201-1-RR
Clone No.241832H4

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

IFN-gamma-R-alpha, IFN-gamma-R1, IFN-gamma receptor 1, IFN-gamma R1, CD119

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive FC detected inmouse splenocytes

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98201-1-RR targets IFNGR1/CD119 in FC applications and shows reactivity with mouse samples.

Tested Reactivity mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein Predict reactive species
Full Name interferon gamma receptor 1
Calculated Molecular Weight52kDa
GenBank Accession NumberNM_010511.3
Gene Symbol Ifngr1
Gene ID (NCBI) 15979
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP15261
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

Background Information

Interferon-gamam (IFN-γ) is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Cellular responses to IFN-γ are activated through its interaction with a heterodimeric receptor consisting of two subunits, IFNGR1 (CD119) and IFNGR2. IFNGR1 is the ligand-binding subunit which binds IFN-γ with high affinity, whereas IFNGR2 serves as the accessory subunit. Two subunits bind one IFN-γ dimer. Defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. (PMID: 17981204; 946248; 10888113)

Protocols

Product Specific Protocols
FC protocol for IFNGR1/CD119 antibody 98201-1-RRDownload protocol
Standard Protocols
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