- Featured Product
- KD/KO Validated
CCS Monoclonal antibody, PBS Only
CCS Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human, mouse, rat
Applications
WB, IHC, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3F5E5
Cat no : 68341-1-PBS
Synonyms
Validation Data Gallery
Product Information
68341-1-PBS targets CCS in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | CCS fusion protein Ag18860 |
Full Name | copper chaperone for superoxide dismutase |
Calculated Molecular Weight | 274 aa, 29 kDa |
Observed Molecular Weight | 32 kDa |
GenBank Accession Number | BC105016 |
Gene Symbol | CCS |
Gene ID (NCBI) | 9973 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Copper chaperone for superoxide dismutase (CCS) is a soluble factor that converts copper into copper-zinc superoxide dismutase ( SOD1 ). CCS and SOD1 interact directly in vivo and in vitro, and this interaction is mediated by homologous domains in each protein. CCS not only interacts with wild-type SOD1 but also interacts with SOD1 containing common missense mutations, resulting in FALS.