CBX6 Polyclonal antibody, PBS Only

CBX6 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 23426-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis of HepG2 using 23426-1-AP (same clone as 23426-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 23426-1-AP (CBX6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23426-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 23426-1-AP (same clone as 23426-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 23426-1-AP (CBX6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23426-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HepG2 using 23426-1-AP (same clone as 23426-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 23426-1-AP (CBX6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23426-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HepG2 using 23426-1-AP (same clone as 23426-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 23426-1-AP (CBX6 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23426-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 23426-1-AP (same clone as 23426-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin slide using 23426-1-AP (CBX6 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 23426-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 23426-1-AP (same clone as 23426-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin slide using 23426-1-AP (CBX6 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 23426-1-PBS in a different storage buffer formulation.

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Product Information

23426-1-PBS targets CBX6 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: CBX6 fusion protein Ag20014
• Full Name: chromobox homolog 6
• Calculated Molecular Weight: 412 aa, 44 kDa
• Observed Molecular Weight: 55-60 kDa
• GenBank Accession Number: BC064900
• Gene Symbol: CBX6
• Gene ID (NCBI): 23466
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

The Chromobox domain (Cbx) gene family, consisting of Polycomb and Heterochromatin Protein 1 genes, involves in transcriptional repression, cell cycle regulation and chromatin remodeling [PMID: 17486619]. Cbx6, other named neuronal pentraxin receptor (NPR), first described as a putative integral membrane pentraxin that interacts with neuronal pentraxin 1 and 2, has also been classified as a Pc protein [PMID: 14647293]. NPR was determined to be a member of a distinct pentraxin protein subfamily, and found to form heteropentamer swithNP1 andNP2, followed by release from cell membranes [PMID: 10748068].