Product Information
67412-1-PBS targets CAP2 in WB, Indirect ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | CAP2 fusion protein Ag8622 Predict reactive species |
Full Name | CAP, adenylate cyclase-associated protein, 2 (yeast) |
Calculated Molecular Weight | 477 aa, 53 kDa |
Observed Molecular Weight | 51-53 kDa |
GenBank Accession Number | BC008481 |
Gene Symbol | CAP2 |
Gene ID (NCBI) | 10486 |
RRID | AB_2882653 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P40123 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CAPs (CAP1 and CAP2) are evolutionarily conserved proteins with roles in regulating the actin cytoskeleton and in signal transduction. CAP2 is predominantly expressed in brain, heart and skeletal muscle, and skin. It is found in the nucleus in undifferentiated myoblasts and at the M-line of differentiated myotubes. Overexpression of CAP2 has been reported in many cancers, including hepatocellular carcinoma (HCC), human breast cancer, and malignant melanoma.