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CAMK4 Monoclonal antibody, PBS Only

CAMK4 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G7A7

Cat no : 68452-1-PBS

Synonyms

CaM kinase GR, CaMK GR, CaMK IV, CAMK4

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using CAMK4 Monoclonal antibody (68452-1-Ig)

    WB analysis using 68452-1-Ig (same clone as 68452-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68452-1-Ig (CAMK4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68452-1-PBS in a different storage buffer formulation.

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

68452-1-PBS targets CAMK4 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Reactivity Human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen CAMK4 fusion protein Ag33332
Full Name calcium/calmodulin-dependent protein kinase IV
Calculated Molecular Weight 473 aa, 52 kDa
Observed Molecular Weight56-65 kDa
GenBank Accession NumberBC025687
Gene Symbol CAMK4
Gene ID (NCBI) 814
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CaMK4 (Calcium/calmodulin-dependent protein kinase IV) is a multifunctional serine/threonine kinase that regulates gene expression by activating transcription factors in a wide range of immune cells including T cells and antigen-presenting cells. The function of CaMK4 is suggested to be abnormal mainly in systemic lupus erythematosus (SLE), which is characterized by autoantibody production, immune complex formation, and immune dysregulation (PMID: 29252071). CaMKIV can translocate between the nucleus and cytoplasm (PMID: 21301225)