CA3 Monoclonal antibody, PBS Only

CA3 Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 66608-1-PBS
Clone No.3C10A2

Host / Isotype

Mouse / IgG2b

Reactivity

human, mouse, rat, pig, rabbit

Applications

WB, IHC, IF-P, Indirect ELISA

Carbonic anhydrase III, Car3, CA-III, CAIII, CA III

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

66608-1-PBS targets CA3 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.

Tested Reactivity human, mouse, rat, pig, rabbit
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen CA3 fusion protein Ag7513 Predict reactive species
Full Name carbonic anhydrase III, muscle specific
Calculated Molecular Weight 29 kDa
Observed Molecular Weight 29 kDa
GenBank Accession NumberBC004897
Gene Symbol CA3
Gene ID (NCBI) 761
RRIDAB_2881968
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP07451
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Carbonic anhydrase III (CA3), which belongs to the alpha-carbonic anhydrase family, is a cytoplasmic enzyme that exhibits a relatively low carbon dioxide hydratase activity. It is expressed at a very high level in skeletal muscle, where physical exercise has been shown to increase free radical production. In addition to its carbon dioxide hydratase activity, CA3 has been demonstrated to have a carboxyl esterase activity and phosphatase activity, which suggests that it is a tyrosine phosphatase (PMID: 10064618). CA3 was found to be localized in Type-I muscle fibers and could be used as a marker for abnormal Type-I muscle fibers in several neuromuscular diseases (PMID: 6221502).

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