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Beta Arrestin 2 Recombinant antibody, PBS Only (Detector)

Beta Arrestin 2 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241470F8

Cat no : 82780-6-PBS

Synonyms

ARRB2, β-Arrestin 2, BARR2, Arrestin beta-2, ARR2

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using Beta Arrestin 2 Recombinant antibody (82780-6-RR)

    WB analysis using 82780-6-RR (same clone as 82780-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82780-6-RR (Beta Arrestin 2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82780-6-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP01125-3

    Cytometric bead array standard curve of MP01125-3

    Cytometric bead array standard curve of MP01125-3, Beta Arrestin 2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82780-5-PBS. Detection antibody: 82780-6-PBS. Standard: Ag0227. Range: 0.781-100 ng/mL.

  • Affinity and Kinetic Characterization of 82780-6-RR

    Affinity and Kinetic Characterization of 82780-6-RR

    Biolayer interferometry (BLl) kinetic assays of 82780-6-RR against Human Beta Arrestin 2 were performed. The affinity constant is below 1 pM.

Product Information

82780-6-PBS targets Beta Arrestin 2 as part of a matched antibody pair:

MP01125-3: 82780-5-PBS capture and 82780-6-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Beta Arrestin 2 fusion protein Ag0227
Full Name arrestin, beta 2
Calculated Molecular Weight 46 kDa
Observed Molecular Weight47-50 kDa
GenBank Accession NumberBC007427
Gene Symbol Beta Arrestin 2
Gene ID (NCBI) 409
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Beta Arrestin 2 is a member of arrestin/beta-arrestin protein family, which are expressed at high levels in the central nervous system (CNS) and play a critical role in the regulation of G-protein coupled receptors (GPCRs) including MOR. Beta Arrestin 2 is an adaptor protein that is important for the regulation of receptors belonging to both dopaminergic and opioid systems. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.