Product Information
15361-1-PBS targets Beta Arrestin 1 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Beta Arrestin 1 fusion protein Ag7608 Predict reactive species |
Full Name | arrestin, beta 1 |
Calculated Molecular Weight | 47 kDa |
Observed Molecular Weight | 47-55 kDa |
GenBank Accession Number | BC003636 |
Gene Symbol | Beta Arrestin 1 |
Gene ID (NCBI) | 408 |
RRID | AB_2060227 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P49407 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
β-Arrestins (ARRBs), the best known regulators of G protein-coupled receptor signaling, are versatile and multifunctional adapter proteins that regulate diverse cellular functions, including cell growth, apoptosis and immune responses. Overexpression of beta Arrestin 1 has been found in various cancers, indicating it as a potential therapeutic target for cancer treatment. Recently expression of ARRB1 in saliva has been identified as a candidate circadian biomarker. ARRB1 migrated as a doublet of two bands of 45 and 55 kDa (PMID:28947386).