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Anti-Human Beta-2-Microglobulin Rabbit Recombinant Antibody, PBS Only

Beta-2-Microglobulin Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241308D5

Cat no : 98165-1-PBS

Synonyms

B2M, 241308D5, HDCMA22P, CDABP0092, Beta-2-microglobulin form pI 5.3

Validation Data Gallery

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  • Flow cytometry (FC) experiment of human peripheral blood leukocytes using Anti-Human Beta-2-Microglobulin Rabbit Recombinant (98165-1-RR)

    FC experiment of human peripheral blood leukocytes using 98165-1-RR (same clone as 98165-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human B2M Rabbit Recombinant Antibody (98165-1-RR, Clone:241308D5) or 0.25 ug Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98165-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98165-1-RR

    Affinity and Kinetic Characterization of 98165-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98165-1-RR against Human Beta-2-Microglobulin were performed. The affinity constant is 2.13 nM.

Product Information

The immunogen of 98165-1-PBS is Beta-2-Microglobulin Fusion Protein expressed in E. coli.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Fusion Protein
Full Name beta-2-microglobulin
Calculated Molecular Weight 119 aa, 14 kDa
GenBank Accession NumberBC032589
Gene Symbol B2M
Gene ID (NCBI) 567
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Beta-2-microglobulin (B2M) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions due to shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.