- Featured Product
- KD/KO Validated
BMI1 Monoclonal antibody, PBS Only
BMI1 Monoclonal Antibody for WB, IHC, IF/ICC, IP, ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human, mouse, monkey
Applications
WB, IHC, IF/ICC, IP, ELISA
Conjugate
Unconjugated
CloneNo.
2E10A11
Cat no : 66161-1-PBS
Synonyms
Validation Data Gallery
Product Information
66161-1-PBS targets BMI1 in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse, monkey samples.
Tested Reactivity | human, mouse, monkey |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | BMI1 fusion protein Ag21284 |
Full Name | BMI1 polycomb ring finger oncogene |
Calculated Molecular Weight | 37 kDa |
Observed Molecular Weight | 37-43 kDa |
GenBank Accession Number | BC011652 |
Gene Symbol | BMI1 |
Gene ID (NCBI) | 648 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody reacts with the 37kd BMI1 protein.