Product Information
66773-1-PBS targets Apolipoprotein A II/APOA2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | Apolipoprotein A II/APOA2 fusion protein Ag9863 Predict reactive species |
Full Name | apolipoprotein A-II |
Calculated Molecular Weight | 100 aa, 11 kDa |
Observed Molecular Weight | 8-11 kDa |
GenBank Accession Number | BC005282 |
Gene Symbol | APOA2 |
Gene ID (NCBI) | 336 |
RRID | AB_2882119 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P02652 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Apolipoprotein A-II (APOA2) is a major component of high density lipoprotein (HDL) and it plays an important role in directing the fate of lipid metabolism among HDL. It is primarily synthesized by liver. The predicted MW of ApoA2 is 11 kDa, while the mature form is smaller (7-10 kDa) since the signal peptide was cleaved. In humans, most of circulating apoA2 exist as dimer. Five types of APOA2 dimer exist: homodimer apoA2-ATQ/ATQ, heterodimer apoA2-ATQ/AT, homodimer apoA2-AT/AT, apoA2-AT/A, and apoA2-A/A. ApoA2 isoforms are considered to be some of the most promising serum/plasma biomarkers for aiding the early detection of pancreatic cancer. (PMID: 29081441, 29481802)