ATP1A1/2 Monoclonal antibody, PBS Only

ATP1A1/2 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 68505-1-PBS
Clone No.3D8G1

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, pig

Applications

WB, IF/ICC, Indirect ELISA

ATP1A2, Na(+)/K(+) ATPase alpha-2 subunit, EC:7.2.2.13, ATP1A 2, alpha 2 ATPase

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

68505-1-PBS targets ATP1A1/2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

Tested Reactivity human, mouse, rat, pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen ATP1A1/2 fusion protein Ag10489 Predict reactive species
Full Name ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide
Calculated Molecular Weight 1020 aa, 112 kDa
Observed Molecular Weight 97-100 kDa
GenBank Accession NumberBC052271
Gene Symbol ATP1A2
Gene ID (NCBI) 477
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP50993
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ATP1A1/2 is the catalytic component of the active enzyme Na+/K+-ATPase, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. The Na+/K+-ATPase is composed of a larger catalytic α-subunit (~110 kDa) and a small β-subunit (~55 kDa). The α subunit has four isoforms identified to date: α1, α2, α3 and α4.The α1 isoform is expressed ubiquitously but the α2 isoform is present largely in the skeletal muscle, heart and vascular smooth muscle. The α3 isoform is found almost exclusively in neurons and ovaries. The α4 isoform is expressed in sperm. This antibody can recognize ATP1A1 and ATP1A2.

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