Product Information
68069-1-PBS targets ARF1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with rabbit, pig, rat, mouse, human samples.
Tested Reactivity | rabbit, pig, rat, mouse, human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | ARF1 fusion protein Ag28021 Predict reactive species |
Full Name | ADP-ribosylation factor 1 |
Calculated Molecular Weight | 21 kDa |
Observed Molecular Weight | 18-21 kDa |
GenBank Accession Number | BC009247 |
Gene Symbol | ARF1 |
Gene ID (NCBI) | 375 |
RRID | AB_2918810 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P84077 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
ADP-ribosylation factors (ARFs) are members of the ARF family of GTP-binding proteins of the Ras superfamily. ARFs bind and regulate GTP/GDP cycle by alternating between the active GTP-bound and inactive GDP-bound conformations. ARF family proteins are essential and ubiquitous in eukaryotes. Six highly conserved members of the family have been identified in mammalian cells. They function in vesicular traffic and actin remodelling and other bioprocesses in cells. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. It mainly functions in coat recruitment.(PMID: 7759471, PMID: 16042562).