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CoraLite®594-conjugated ARC Monoclonal antibody

ARC Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse, Rat, Pig, rabbit

Applications

IF/ICC

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

1G4B5

Cat no : CL594-66550

Synonyms

ARC, ARC/ARG3.1, Arg3.1, KIAA0278



Tested Applications

Positive IF/ICC detected inSH-SY5Y cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL594-66550 targets ARC in IF/ICC applications and shows reactivity with Human, Mouse, Rat, Pig, rabbit samples.

Tested Reactivity Human, Mouse, Rat, Pig, rabbit
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen ARC fusion protein Ag9445
Full Name activity-regulated cytoskeleton-associated protein
Calculated Molecular Weight 396 aa, 45 kDa
Observed Molecular Weight 50 kDa
GenBank Accession NumberBC012321
Gene Symbol ARC
Gene ID (NCBI) 23237
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission Maxima Wavelengths588 nm / 604 nm
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ARC, also named as KIAA0278 and Arg3.1, mediates endocytosis of neuronal AMPA-type glutamate receptors (AMPARs). It is required for consolidation of synaptic plasticity as well as formation of long-term memory. ARC plays a role in the regulation of cell morphology and cytoskeletal organization. It is required in the stress fiber dynamics and cell migration. Recent study shows that expression of Arc can regulate cognitive flexibility.

Protocols

Product Specific Protocols
IF protocol for CL594 ARC antibody CL594-66550Download protocol
Standard Protocols
Click here to view our Standard Protocols