CoraLite®594-conjugated ALDH1L1 Monoclonal antibody

ALDH1L1 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat, mouse, pig

Applications

IF-P

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

1C1A3

Cat no : CL594-68018

Synonyms

10 FTHFDH, ALDH1L1, DKFZp781N0997, FTHFD

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Validation Data Gallery

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  IF Staining of mouse brain using CL594-68018

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite®594 ALDH1L1 antibody (CL594-68018, Clone: 1C1A3 ) at dilution of 1:200.

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Tested Applications

• Positive IF-P detected in: mouse brain tissue

Recommended dilution

• Immunofluorescence (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

CL594-68018 targets ALDH1L1 in IF-P applications and shows reactivity with Human, rat, mouse, pig samples.

• Tested Reactivity: Human, rat, mouse, pig
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: ALDH1L1 fusion protein Ag13190
• Full Name: aldehyde dehydrogenase 1 family, member L1
• Calculated Molecular Weight: 99 kDa
• Observed Molecular Weight: 100 kDa
• GenBank Accession Number: BC027241
• Gene Symbol: ALDH1L1
• Gene ID (NCBI): 10840
• Conjugate: CoraLite®594 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 588 nm / 604 nm
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
• Storage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Background Information

Aldehyde dehydrogenase 1 family member L1 (ALDH1L1), belongs to the aldehyde dehydrogenase family of proteins and is responsible for formate oxidation in vivo. Loss of ALDH1L1 is associated with decreased apoptosis, increased cell motility, and cancer progression. ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. ALDH1L1 has some isoforms with MW of 99, 88 and 55 kDa.