AGXT2L1 Recombinant antibody, PBS Only

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  IHC staining of mouse liver using 83984-5-RR (same clone as 83984-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 83984-5-RR (AGXT2L1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83984-5-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 83984-5-RR (same clone as 83984-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 83984-5-RR (AGXT2L1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83984-5-PBS in a different storage buffer formulation.

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  IF Staining of U2OS using 83984-5-RR (same clone as 83984-5-PBS)

  Immunofluorescent analysis of (4% PFA) fixed U2OS cells using AGXT2L1 antibody (83984-5-RR, Clone: 241119H5 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 83984-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83984-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83984-5-RR against Human AGXT2L1 were performed. The affinity constant is 1.77 nM.

AGXT2L1 {ptg:Brand} Recombinant Antibody for IHC, IF/ICC, ELISA

Cat No. 83984-5-PBS

Clone No.241119H5

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF/ICC, ELISA

Synonyms

ETNPPL, Ethanolamine-phosphate phospho-lyase, EC:4.2.3.2, Alanine--glyoxylate aminotransferase 2-like 1, 241119H5

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Product Information

83984-5-PBS targets AGXT2L1 in IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: AGXT2L1 fusion protein Ag10584
• Full Name: alanine-glyoxylate aminotransferase 2-like 1
• Calculated Molecular Weight: 499 aa, 56 kDa
• GenBank Accession Number: BC022526
• Gene Symbol: AGXT2L1
• Gene ID (NCBI): 64850
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q8TBG4
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

Alanine-glyoxylate aminotransferase 2-like 1 (AGXT2L1), also called ethanolamine phosphate phospholyase (ETNPPL), is a brain enzyme, so-named after its similarity to AGXT2 (36% sequence identity), that may be involved in the pathogenesis of severe neuropsychiatric disturbances(PMID: 23761375). AGXT2L1 is significantly down-regulated in cancerous tissues and may be a tumor suppressor(PMID: 26294768,