AEBP2 Monoclonal antibody, PBS Only

AEBP2 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, pig

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

7H2B11

Cat no : 66141-1-PBS

Synonyms

AE binding protein 2, AEBP2, Zinc finger protein AEBP2

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Validation Data Gallery

• 

  WB analysis of HeLa using 66141-1-Ig (same clone as 66141-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 66141-1-Ig (AEBP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66141-1-PBS in a different storage buffer formulation.

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Product Information

66141-1-PBS targets AEBP2 in WB, ELISA applications and shows reactivity with human, pig samples.

• Tested Reactivity: human, pig
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: AEBP2 fusion protein Ag17905
• Full Name: AE binding protein 2
• Calculated Molecular Weight: 33 kDa, 54 kDa
• Observed Molecular Weight: 55 kDa
• GenBank Accession Number: BC015624
• Gene Symbol: AEBP2
• Gene ID (NCBI): 121536
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS only
• Storage Conditions: Store at -80°C.

Background Information

AEBP2 belongs to the AEBP2/jing C2H2-type zinc-finger family. It is a DNA-binding transcriptional repressor. AEBP2 is a zinc finger protein that has been shown to interact with the mammalian Polycomb Repression Complex 2 (PRC2). It may interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3. AEBP2 is an evolutionarily well-conserved gene that is found in the animals ranging from flying insects to mammals. (PMID:19293275) The antibody recognizes adult-specific larger form (52 kDa) and the embryo-specific smaller form (31 kDa).